THE MOST POPULAR DIABETIC DOCTORS NEAR ME Causes of Diabetic Foot Pain and Ulcers Diabetic ulcers are most commonly caused by: poor circulation high blood sugar (hyperglycemia) nerve damage irritated or wounded feet Poor blood circulation is a form of vascular disease in which blood doesn’t flow to your feet efficiently. Poor circulation can also make it more difficult for ulcers to heal. High glucose levels can slow down the healing process of an infected foot ulcer, so blood sugar management is critical. People with type 2 diabetes often have a harder time fighting off infections from ulcers. Nerve damage is a long-term effect and can even lead to a loss of feeling in your feet. Damaged nerves can feel tingly and painful at first. Nerve damage reduces your sensitivity to foot pain and results in painless wounds that can cause ulcers. Ulcers can be identified by drainage from the affected area and sometimes a noticeable lump that isn’t always painful.