Diabetes clinics in Bettahalasur, Bangalore • The genetic dyslipidaemias Disorder Defect Lipoprotein elevation Clinical findings Pattern Drug treatment Familial chylomicronaemia Lipoprotein lipase defect Chylomicrons Eruptive xanthomata Pancreatitis I None Familial chylomicronaemia Apolipoprotein CII deficiency Chylomicrons, VLDL Pancreatitis I, V None Familial type III (dysbetalipoproteinaemia) Apolipoprotein BIE receptor deficiency Chylomicron remnants Eruptive xanthomata Atherosclerosis III IIa, IIb IV Fibrates Statins Nicotinic acid Familial hypercholestrolaemia (AUTO DOM 1:1500) Deficient LDL receptor LDL Xanthomata Atherosclerosis IIa Resin Statins Familial hypertriglyceridaemia Defect unknown VLDL Xanthomata IV Fibrates Nicotinic acid Multiple lipoprotein hyperlipidaemia Defect unknown LDL, VLDL Atherosclerosis IIa, IIb IV Fibrates Nicotinic acid Statins AUTO DOM = autosomal dominant inheritance; LDL = low-density lipoproteins; VLDL = very low-density lipoproteins.