best cardiac doctors in Yelahanka What are the 4 signs of heart failure Heart failure signs and symptoms may include: Shortness of breath with activity or when lying down. Fatigue and weakness. Swelling in the legs, ankles and feet. Rapid or irregular heartbeat. Reduced ability to exercise. Persistent cough or wheezing with white or pink blood-tinged mucus. Swelling of the belly area (abdomen)